The Ohio State Buckeyes have gotten some very positive injury news heading into their inaugural Big Ten conference game. Pete Thamel of ESPN has reported that Ohio State defensive lineman Tyleik Williams will play against the Michigan State Spartans on Saturday after missing last week's game against the Marshall Thundering Herd with an undisclosed injury.

The Ohio State Buckeyes beat the Michigan State Spartans last year 38-3. Get tickets to the rematch. SeatGeek, Stubhub, Vivid Seats and Ticketmaster have tickets to the game starting at $42. The Michigan State Spartans (3-1) lost to the Boston College Eagles, 19-23. The Ohio State Buckeyes (3-0) defeated the Marshall Thundering Herd 49-14.

Even though the first three games counted, it feels like the preseason is over for Ohio State and now the real work begins. The Buckeyes have done exactly what they were supposed to do in dismantling Akron,

You got to go out there and believe because if you don’t believe, you don’t have a chance,” linebacker Cal Haladay said.

The stakes are higher in Week 5 for Ohio State as it faces its first Big Ten opponent of the season. And the third-ranked Buckeyes will do so away from the friendly confines of Ohio Stadium under the lights at Michigan State.

Get ready for our Ohio State vs. Michigan State betting preview for updated odds, predictions, and insights on whether the Buckeyes will cover the spread.

Stephen Means, Stefan Krajisnik and Andrew Gillis give their game predictions for Ohio State football's game against Michigan State.